Nuclear medicine

 

Nuclear medicine

Radioactivity for diagnosis and therapy 

De Richard Zimmermann 

EDP Sciences - Collection : Hors Collection - 2e édition - septembre 2017

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Présentation 

Nuclear medicine is a growing specialized medical field in which radiopharmaceuticals, i.e. drugs associated to radioactivity, are used for diagnostic or therapeutic purposes. Since 1942, nuclear medicine has progressed in such a way that it became a major diagnostic tool in hospitals. The past ten years have seen the introduction of major technical breakthroughs which will considerably modify the landscape of cancer treatment.

Once injected to the patient, the radiopharmaceutical drug aims at the tumour cell – including metastases – selectively, settles there, and emits radiation. Depending on the radiation type, the drug will either help identify the cells or destroy them. Applications are not limited to oncology; indeed, nuclear medicine has found interesting applications in cardiology and neurology as well.

The new millennium saw the introduction of the Hybrid imaging technology PET/CT which combines the Positron Emission Tomography (PET) modality with conventional high quality x-ray imaging. It took another two years until PET could be combined with Magnetic Resonance Imaging (MRI) in the hybrid equipment PET/MR. New tracers (drugs for diagnosis) also came on the market with different diseases as targets, such as prostate cancer, neuroendocrine tumours, or Alzheimer’s disease. But the recent introduction of radiotherapeutics in the treatment of cancer has brought major changes on the market, for they can be much more powerful and specific than chemotherapeutics or external radiation therapy. Combining radiodiagnostics to select positive responders to a treatment with efficient radiotherapeutics opens a highway for the development of theranostics, another word for personalized medicine.

This scientific book aims to introduce nuclear medicine to a larger audience, pointing out, among other things, the difficulties met by both physicians and patients when trying to access new technologies. This second edition shows how much progress has been made over the past ten years since the original book was published, and how much can be expected for patients within the next few years.

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Astrophysics of Gaseous Nebulae by Donald E. Osterbr...

Astrophysics of Gaseous Nebulae by Donald E. Osterbr...

Thoroughly revised and expanded throughout, the new edition is a graduate-level text and reference book on gaseous nebulae, nova and supernova remnants. Much of the new data and new images are from the Hubble Space Telescope with two wholly new chapters being added along with other new features. The previous edition which was tried and tested for thirty years has now been succeeded by a revised, updated, larger edition, which will be valuable to anyone seriously interested in astrophysics.

Table des matières

General Introduction	1
1	7
1	13
Thermal Equilibrium	45
Calculation of Emitted Spectrum	67
Comparison of Theory with Observations	107
Internal Dynamics of Gaseous Nebulae	157
Infrared Radiation and Molecules	207

Heavy Elements and HighEnergy Effects	277
Nova and Supernova Remnants	295
Active Galactic NucleiDiagnostics and Physics	325
Active Galactic NucleiResults	353
Appendix J Measures of Light	395
Appendix Milne Relation Between Capture and Photoionization Cross	401
Appendix TT Nebular Quantum Mechanics	407
Atomic Data for Heavy Element Ionization Balance	423

4	214
Planetary Nebulae	247

Appendix Q Quantum Mechanics of Molecules	433
Droits d'auteur

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astrophysics for people in a hurry

astrophysics for people in a hurry

Cosmos is one of the bestselling science books of all time. In clear-eyed prose, Sagan reveals a jewel-like blue world inhabited by a life form that is just beginning to discover its own identity and to venture into the vast ocean of space. Featuring a new Introduction by Sagan’s collaborator, Ann Druyan, full color illustrations, and a new Foreword by astrophysicist Neil deGrasse Tyson, Cosmos retraces the fourteen billion years of cosmic evolution that have transformed matter into consciousness, exploring such topics as the origin of life, the human brain, Egyptian hieroglyphics, spacecraft missions, the death of the Sun, the evolution of galaxies, and the forces and individuals who helped to shape modern science.

Praise for Cosmos
 
“Magnificent . . . With a lyrical literary style, and a range that touches almost all aspects of human knowledge, Cosmos often seems too good to be true.”—The Plain Dealer
 
“Sagan is an astronomer with one eye on the stars, another on history, and a third—his mind’s—on the human condition.”—Newsday
 
“Brilliant in its scope and provocative in its suggestions . . . shimmers with a sense of wonder.”—The Miami Herald
 
“Sagan dazzles the mind with the miracle of our survival, framed by the stately galaxies of space.”—Cosmopolitan
 
“Enticing . . . iridescent . . . imaginatively illustrated.”—The New York Times Book Review

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Tainted: A Young Adult Dystopian Series (The ARC Book 1) Kindle Edition

Tainted: A Young Adult Dystopian Series (The ARC Book 1) Kindle Edition

Elle Winters lost everything when the day of impact transformed Earth's surface into an icy, desolate wasteland. All she has ever known are the artificial confines of underground fallout shelter, the ARC. Under the Council's rule, ruthless officials roam the hallways, community comes first and everyone lives in fear of failing their annual testing. With one simple blood test you could be taken away without any warning or a word of goodbye. 

There are only a few people in the ARC who Elle truly cares about and she desperately tries to keep them at arm's length away for fear of losing someone else. Especially, her best friend Sebastian who she denies her feelings for, even from herself. 

Chilling secrets and mysterious disappearances plague the ARC, but Elle would never dare to voice the forbidden questions that linger on her lips. That is until they take the wrong person. 

No one is truly safe in the ARC and Elle is about to experience her own personal apocalypse. With nothing left to lose she will risk everything to uncover the truth about the tainted. 

Will she find what she's looking for or are some secrets better left buried deep underground? 

Don't miss the first book in this young adult series!

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The Year's Best Science Fiction: Twenty-Seventh Annual Collection

The Year's Best Science Fiction: Twenty-Seventh Annual Collection

The thirty-two stories in this collection imaginatively take us far across the universe, into the very core of our beings, to the realm of the gods, and the moment just after now. Included here are the works of masters of the form and of bright new talents, including:

John Barnes, Elizabeth Bear, Damien Broderick, Karl Bunker, Paul Cornell, Albert E. Cowdrey, Ian Creasey, Steven Gould, Dominic Green, Nicola Griffith, Alexander Irvine, John Kessel, Ted Kosmatka, Nancy Kress, Jay Lake, Rand B. Lee, Paul McAuley, Ian McDonald, Maureen F. McHugh, Sarah Monette, Michael Poore, Robert Reed, Adam Roberts, Chris Roberson, Mary Rosenblum, Geoff Ryman, Vandana Singh, Bruce Sterling, Lavie Tidhar, James Van Pelt, Jo Walton, Peter Watts, Robert Charles Wilson, and John C. Wright.

Supplementing the stories are the editor's insightful summation of the year's events and a lengthy list of honorable mentions, making this book both a valuable resource and the single best place in the universe to find stories that stir the imagination, and the heart.

From Publishers Weekly

Continuing the annual tradition, award-winning editor Dozois selects 32 of 2009's strongest short fiction pieces from print and online venues. The authors of these stories are almost all experienced and prolific, with many award winners and few surprise newcomers to be found. The offerings run the gamut of science fiction: for example, Nicola Griffith's "It Takes Two" explores love through chemical attraction, John Barnes's "Things Undone" is a time-blurring exploration of alternate history, and John Kessel's "Events Preceding the Helvetican Renaissance" is a far-future adventure. This smorgasbord of thought-provoking fiction ensures that any reader will likely find something appealing. Rounding out the collection is Dozois's writeup of all things 2009 SF: fiction, nonfiction, media, awards, and obituaries. 

Review

“This smorgasbord of thought-provoking fiction ensures that any reader will likely find something appealing.” ―Publishers Weekly

“Gardner Dozois's long-running "best of" series is rightly a favorite...The Year's Best Science Fiction: Twenty-Seventh Annual Collection, for all its bulk, is charmingly eclectic...Mr. Dozois picks fiction that deserves to be better known to a wide audience.” ―The Wall Street Journal

“This is a worthy addition to a venerable series.” ―Publishers Weekly on The Year's Best Science Fiction: Twenty-sixth Annual Collection

“For more than a quarter century, Gardner Dozois's The Year's Best Science Fiction has defined the field. It is the most important anthology, not only annually, but overall.” ―Charles N. Brown, publisher of Locus Magazine on The Year’s Best Science Fiction: Twenty-sixth Annual Collection

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The Year's Best Science Fiction: Twenty-Sixth Annual Collection

The Year's Best Science Fiction: Twenty-Sixth Annual Collection

The thirty stories in this collection imaginatively take us far across the universe, into the very core of our beings, to the realm of the gods, and the moment just after now. Included here are the works of masters of the form and of bright new talents, including: Paolo Bacigalupi, Stephen Baxter, Elizabeth Bear, Aliete de Bodard, James L. Cambias, Greg Egan, Charles Coleman Finlay, James Alan Gardner, Dominic Green, Daryl Gregory, Gwyneth Jones, Ted Kosmatka, Mary Robinette Kowal, Nancy Kress, Jay Lake, Paul McAuley, Ian McDonald, Maureen McHugh, Sarah Monette, Garth Nix, Hannu Rajaniemi, Robert Reed, Alastair Reynolds, Mary Rosenblum, Kristine Kathryn Rusch, Geoff Ryman, Karl Schroeder, Gord Sellar, and Michael Swanwick.

Supplementing the stories are the editor's insightful summation of the year's events and a lengthy list of honorable mentions, making this book both a valuable resource and the single best place in the universe to find stories that stir the imagination, and the heart.

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